ISNO was founded in 1993 and is a Dutch initiative which aims to stimulate and facilitate research and to improve treatment of neuromuscular disorders. It forms a platform bringing together Dutch neuromuscular specialists and researchers in a network of exellence.

Different activities of ISNO are:

- CRAMP database
- Yearly neuromuscular symposium
- Inform neurologists of neuromuscular trials in the Netherlands
- Neuromyologist Fellow curriculum
- Stimulate collaboration between the different neuromuscular centres